Lung cancer treatments, including chemotherapy, radiation therapy, immunotherapy, and targeted therapy, may cause skin reactions that can range from mild to severe. You may notice a rash, redness, very dry skin, changes in your nails, or changes in your hair. These effects are usually temporary.

• Chemotherapy can cause dry, itchy skin, and can lower the level of platelets (tiny fragments of cells that help stop bleeding) in the blood, causing easy bruising and bleeding.
• Radiation therapy can cause sunburn-like redness where the beams come into contact with the skin. It can be painful and can sometimes result in open sores.
• Immunotherapy can cause dry, itchy skin and less commonly, rash and blisters.
• Targeted therapies can cause a rash, itching, and/or dryness, depending on the specific type of targeted therapy given.

Rashes, dryness, and other skin reactions can be uncomfortable, but there are ways you can manage mild issues at home after talking with your healthcare team.

Practical tips:

• Use mild soaps, pat your skin dry, and use a sensitive skin moisturizer before a rash appears.
• Protect your skin from heat and cold.
• Protect your skin from direct sunlight.
• Wear loose, soft clothing.
• Avoid using skin products right before your radiation therapy.

It’s always a good idea to tell a member of your healthcare team when you notice a side effect from treatment or a symptom that concerns you. Often, these problems can be prevented or eased with help from your healthcare team or through palliative care services. Skin reactions are a common side effect that are often easily treated. Talk to your healthcare team as soon as you start seeing a change in your skin. They may recommend a dermatologist (skin doctor) to discuss treatment options.

If you have a severe, extensive, blistering, or painful rash, contact your healthcare team right away. This is especially important if it involves the eyes or mucous membranes such as your mouth.