Many people being treated for lung cancer will eventually develop resistance to their current therapies, causing them to stop working. When this happens, and a person’s cancer starts to progress on their current treatment, their healthcare team will take a tissue and/or liquid biopsy to access their new treatment needs and decide on the next lung cancer therapy.  

Dr. Jyoti Malhotra from City of Hope joined GO2’s January 2024 Lung Cancer Living Room to discuss the topic of treatment resistance and to explain the options for people experiencing progression, questions they should ask their healthcare team, and when they might want to consider a clinical trial for further treatment.

Speakers: 

  • Jyoti Malhotra, MD, MPH, Director, Thoracic Medical Oncology, Associate Professor, Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center 
  • Danielle Hicks, Chief Patient Officer, GO2 for Lung Cancer 

Discussed in this episode:  

  • After having biomarker testing done to look for biological changes associated with your cancer, your doctor may recommend a targeted therapy or immunotherapy to treat your specific type of lung cancer. 
  • Many promising clinical trials are happening right now, aimed at better treating disease progression. GO2’s LungMATCH service provides personalized help navigating the clinical trial process to understand whether one of these trials might help treat your lung cancer. 

For more information on treatment resistance and cancer progression:  

  • Dr. David Gandera from UC Davis Comprehensive Cancer Center explored the topic of resistance to treatment in the September 2022 episode of the Lung Cancer Living Room.  
  • GO2 experts answered a related question about having another biopsy at the time of progression in the November 22, 2022 Ask the Experts blog.  

Please join us on February 20 at 5:30 p.m. PT/8:30 p.m. ET for the next Lung Cancer Living Room covering women and lung cancer. Join in person at our San Carlos, CA office or watch on YouTube Live.  

For more information on the Living Room, other GO2 for Lung Cancer programs, or support through diagnosis and treatment, please contact GO2’s HelpLine at 1-800-298-2436 or email support@go2.org.