Drugs Targeting NTRK

  • Vitrakvi (larotrectinib) – approved for stage 4 NSCLC patients with a fusion in NTRK as detected by a biomarker test.
  • Rozlytrek (entrectinib) – approved for stage 4 NSCLC patients with a fusion in NTRK as detected by a biomarker test.
  • Augtyro (repotrectinib) – approved for solid tumors, including NSCLC, for adults and children aged 12 years and older with a fusion in NTRK as detected by a biomarker test.