Drugs Targeting ALK
- Alecensa (alectinib) – approved for stage 1B-3A NSCLC patients following complete surgical resection and stage 4 NSCLC patients with a change in ALK as detected by a biomarker test.
- Alunbrig (brigatinib) – approved for stage 4 NSCLC patients with a change in ALK as detected by a biomarker test who have progressed on another ALK targeted therapy.
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Ensacove (ensartinib) – approved for stage 3 and 4 NSCLC patients with a change in ALK, as detected by a biomarker test, and have not been previously given another ALK targeted therapy.
- Lobrena (lorlatinib) – approved for stage 4 NSCLC patients with a change in ALK as detected by a biomarker test and who have progressed on at least two other ALK targeted therapies.
- Xalkori (crizotinib) – approved for stage 4 NSCLC patients with a change in ALK as detected by a biomarker test.
- Zykadia (ceritinib) – approved for stage 4 NSCLC patients with a change in ALK as detected by a biomarker test.